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February 2025

New Paper Out!

Reinstatement and transformation of memory traces for recognition
Episodic memory relies on the formation and retrieval of content-specific memory traces. In addition to their veridical reactivation, previous studies have indicated that traces may undergo substantial transformations. However, the exact time course and regional distribution of reinstatement and transformation during recognition memory have remained unclear. We applied representational similarity analysis to human intracranial electroencephalography to track the spatiotemporal dynamics underlying the reinstatement and transformation of memory traces.

Rau EMB et al. (2025) Reinstatement and transformation of memory traces for recognition. Sci Adv 11(8):eadp9336. doi: 10.1126/sciadv.adp9336

April 2025

New Paper Out!

Characterizing BOLD activation patterns in the human hippocampus with laminar fMRI
The human hippocampus has been extensively studied at the macroscale using functional magnetic resonance imaging (fMRI) but the underlying microcircuits at the mesoscale (i.e., at the level of layers) are largely uninvestigated in humans. We target two questions fundamental to hippocampal laminar fMRI: How does the venous bias affect the interpretation of hippocampal laminar responses, and is it possible to establish a benchmark laminar fMRI experiment which robustly elicits single-subject hippocampal activation utilizing the most widely applied GRE-BOLD contrast.

Pfaffenrot et al. (2025) Characterizing BOLD activation patterns in the human hippocampus with laminar fMRI. Imaging Neurosci 3: imag_a_00532. doi: 10.1162/imag_a_00532